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But my patients were giving me an important clue. People taking GLP-1 drugs often talk about “food noise” vanishing: the constant mental chatter about food that dominated their days simply goes quiet. But my patients were reporting that it wasn’t just food: They were noticing that the preoccupation with smoking, drinking and using drugs that drives people back despite their best intentions to stop was going quiet too.

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The persistence of false beliefs is often attributed to a motivation to be right, but cognitive science research suggests a more fundamental mechanism: the specific strategy humans use in seeking new information. When individuals attempt to discover a rule or verify a belief, they rarely attempt to falsify their own assumptions. Instead, they employ a “positive test strategy,” searching for instances that would occur if their working hypothesis were true [klayman_confirmation_1987, klayman_varieties_1995, bhatia_confirmatory_2014].