当然，风险亦不容忽视。Infigratinib是泛FGFR1-4抑制剂，对FGFR1等的抑制可能引起高磷血症等副作用。3期试验中约有4%患者出现轻度、短暂的高磷血症。在儿科长期用药的背景下，其安全性仍需更严格的监测，监管的要求也会更严格。
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转机出现了，下滚的牛被两棵树挡住，随即弹进了树旁的深坑，卡在坑里喘着粗气。几经周折，这头牛被拉出了坑，但它被重重摔过两次，早没了力气，没走几步路就四仰八叉地下滑，后面卧在沟底不动弹了。
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Uniform regions (solid backgrounds, smooth gradients) get stored as large blocks. Detailed regions (edges, textures) get subdivided into smaller blocks. You end up with a compressed representation that preserves detail where it exists and simplifies where it can.